Washington University in St Louis

The Preston M. Green Department of
Electrical & Systems Engineering

We build novel imaging technologies

Lew Lab group photo

The Lew Lab leverages innovations in applied physics, electrical engineering, computational algorithms, and chemistry to create optical imaging systems with unprecedented performance. We partner with scientists and engineers across all disciplines to develop technologies to solve unmet needs in science, medicine, and society.

The Lew Lab is a team of inventors, thinkers, and problem solvers working at the intersection of science and technology. Meet the members of this team. Excited about joining our team?

Creating impactful technology is our passion

One of our goals is to develop advanced nanoscopes (microscopes with nanometer resolution) that can visualize the activity of molecular machines inside and between living cells. These tools would allow researchers to observe a variety of processes involved in health and disease: viruses invading cells, cells packaging biomolecular cargo to communicate with other cells, and much more. The nanoscopes we build enable us to see activities in the molecular world within living cells that could never be seen before.

Lab news

Kevin's and Tianben's article on super-resolution transient amyloid binding (TAB) microscopy is a featured cover article at ChemBioChem. Congratulations to the entire team! Read it here:
“Super-Resolution Imaging of Amyloid Structures over Extended Times Using Transient Binding of Single Thioflavin T Molecules” [Open Scholarship]
Press coverage: The Source - Washington University, NSF Science360, EurekAlert!

Henry CohenHenry Cohen, who is studying for an MS degree in Biomedical Engineering, has joined the Lew Lab and received a Master's Fellowship. Welcome, Henry!

Hesam's article on the characteristics of structural bias in super-resolution microscopy and how to minimize it using our RoSE algorithm is now online at Scientific Reports. Congratulations! Read it here:
“Minimizing Structural Bias in Single-Molecule Super-Resolution Microscopy”

Weiran WangWeiran Wang, who is studying for an MS degree in Electrical Engineering, has joined the Lew Lab and received a Master's Fellowship. Welcome, Weiran!