We build novel imaging technologies
The Lew Lab builds advanced imaging systems to study biological and chemical systems at the nanoscale. Our technology leverages innovations in applied optics, signal and image processing, design optimization, and physical chemistry. We partner with scientists and engineers across all disciplines to develop technologies to solve unmet needs in science, medicine, and society.
Diversity fosters creative ideas to challenging problems
The Lew Lab is a team of inventors, thinkers, and problem solvers working at the intersection of science and technology.
Creating impactful technology is our passion
Lab news
Congratulations to Ezra and colleagues in the Lee Lab at the University of Cambridge! Their work on simple and computationally efficient molecular orientation microscopy is now online in Nature Methods! It was a saga getting this work completed. Thank you, Oumeng, for demonstrating the accuracy of RoSE-O in analyzing these data!
- Read it here: “POLCAM: instant molecular orientation microscopy for the life sciences”
Weiyan's study of how noise-induced errors limit the accuracy of
measuring how molecules “wobble” in 3 dimensions is now online in
J. Phys. Chem. A!
- Read it here: “Fundamental Limits in
Measuring the Anisotropic Rotational Diffusion of Single Molecules”
- Our work is covered in McKelvey Engineering News: “Wobbly
molecules get a closer look”
- Update: Weiyan's article is featured as a cover of Volume 128,
Issue 28 of
J. Phys. Chem. A!
Brian's study on using the binding orientations of Nile blue to
decipher the architectures of growing, decaying, and remodeling amyloid-beta fibrils is now
online in
Nano Lett.!
- Read it here: “Single-Molecule
Orientation Imaging Reveals the Nano-Architecture of Amyloid Fibrils Undergoing Growth and
Decay”
- Read the accompanying news article, “WashU
researchers shine light on amyloid architecture,” in The Source!
The lab welcomes Erik Lindeman, who received a Caltech Summer Undergraduate Research Fellowship to visit us for a summer project. We're excited to have you!